Purpose-built AI for mental health: real-world outcomes

Ash's Derrick Hull presented at the 2025 McLean Technology in Psychiatry Summit on why a purpose-built foundation model is safer than general AI, plus real-world Ash outcome data.

Technology in Psychiatry Summit, McLean Institute for Technology in Psychiatry

Purpose-built AI for mental health: real-world outcomes (McLean 2025)

Key Finding

A mental-health-specific foundation model showed a substantially safer response profile than general-purpose AI on suicide and self-harm test sets, and real-world Ash use was associated with symptom reduction and improved social support — with more engagement linked to better, not worse, outcomes.

Summary

At the 2025 Technology in Psychiatry Summit (McLean Institute for Technology in Psychiatry), Dr. Derrick Hull, founding Clinical Lead at Ash by Slingshot AI, presented on building a purpose-built foundation model for mental health and on real-world outcomes from Ash. He argued that grounding a model in clinically relevant data yields a markedly safer profile than general-purpose AI, and walked through proof-of-concept findings on symptom reduction, behavioral activation, social support, and working alliance.

The Full Picture

Hull contrasted purpose-built and general-purpose models: training on clinically relevant data lowers the base rate of harmful responses — so guardrails start from a safer baseline — and shifts the model from an information-giving "assistant" stance toward information-gathering and appropriate referral (for example, in OCD or bipolar disorder). On outcomes, he presented proof-of-concept real-world data using latent growth mixture modeling, goal-attainment scaling, behavioral activation, and several social-health measures (perceived social support, social interaction, and outings), noting that interaction volume predicted improvement rather than harm.

He framed the work as early, proof-of-concept evidence and emphasized open questions — appropriate control groups, longer follow-up, and which therapeutic mechanisms AI is best suited to deliver — while disclosing that he is compensated by Slingshot AI.

Researchers

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ACKNOWLEDGMENT

Ash is not designed to be used in crisis. If you are in crisis, please seek out professional help, or a crisis line. You can find resources at www.findahelpline.com.